Gregor Warnecke Institut für Herz-, Thorax-, Transplantations- und Gefäßchirurgie Medizinische Hochschule Hannover 1. Donhauser & Schöneberger, Bingen am Rhein, Germany. NIH Institut für Mikrobiologie und Tierseucben Direktor: Prof. Dr. W. Bisping der Tierärztlichen Hochschule Hannover Tierärztliche Hochschule, 3 Hannover, Bischofsholer Damm 15. (1)Institut für Pathologie, Stiftung Tierärztliche Hochschule Hannover, Hannover, Germany. This site needs JavaScript to work properly. doi: 10.1371/journal.pone.0121586. vet. HHS J. Pohlenz. Would you like email updates of new search results? Dr. med. eCollection 2019 Dec 10. Institut für Pathologie, Tierärztliche Hochschule Hannover, Bischofsholer Damm 15, D‐3000 Hannover 1Search for more papers by this author. Microarray analysis reveals gene and microRNA signatures in diabetic kidney disease. NLM | andreas.beineke@tiho-hannover.de Harbor porpoises from the North and Baltic Seas exhibit a higher incidence of bacterial infections compared to whales from less polluted arctic waters. 2019 Nov 20;8(4):249. doi: 10.3390/pathogens8040249. Fragen der Diagnostik: Geschäftszimmer, Tel.-Nr. 2020 Jul 25;21(15):5289. doi: 10.3390/ijms21155289. COVID-19 is an emerging, rapidly evolving situation. Dr. med. NCI CPTC Antibody Characterization Program. Epub 2018 May 21. 2003 Nov;106(5):486-94. doi: 10.1007/s00401-003-0754-6. This site needs JavaScript to work properly. NLM USA.gov. Vet Immunol Immunopathol. Institute of Microbiology and Infectious Diseases of Animals, School of Veterinary Medicine, Hannover, Germany. We are a leader in research, teaching and services in veterinary medicine and train young scientists in all areas of veterinary science. Uncovering newly emerging variants of Streptococcus suis, an important zoonotic agent. 2000 Feb;99(2):138-46. doi: 10.1007/pl00007417. Hennig-Pauka I, Imker R, Mayer L, Brügmann M, Werckenthin C, Weber H, Menrath A, de Buhr N. Pathogens. Likewise, MMPs and TIMPs are prominently up-regulated in these lesions and are expressed mostly by astrocytes and microglia. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Clinical manifestations related to meningitis, arthritis and serositis could be induced by intravenous application of this serotype 9 strain. Ziel dieser Arbeit war es, festzustellen, ob und wann eine PCV 2-Infektion vor 1998, dem Jahr des erstmaligen Nachweises von PCV 2 in Deutschland, im Sektionsmaterial des Instituts für Pathologie der Stiftung Tierärztliche Hochschule Hannover aufgetreten ist. vet. (1)Institut für Pathologie, Tierärztliche Hochschule Hannover, 30559 Hannover, Germany. It is often referred to as TiHo by its staff and students. Epub 2005 Aug 25. Epub 2010 Jan 12. | This page... Print this page. Prevention and treatment information (HHS). Serotype distribution and production of muramidase-released protein, extracellular factor and suilysin by field strains of Streptococcus suis isolated in the United States. Search for more papers by this author. 2016 Jul;11:941-54. doi: 10.2217/fmb-2016-0028. The present review decribes the role of CD44 antigen (CD44), the principle cell surface receptor for hyaluronate and extracellular matrix (ECM) processing enzymes (matrix metalloproteinases [MMPs]) and their inhibitors (TIMPs) in the pathogenesis of demyelination. | Epub 2009 May 18. Bibliografische Informationen der Deutschen Bibliothek Die Deutsche Bibliothek verzeichnet diese Publikation in der Deutschen Nationalbibliografie; Detaillierte bibliografische Da PLoS One. PLoS One. Streptococcus (S.) suis is an invasive porcine pathogen causing meningitis, septicemia, arthritis and other diseases. Publication History. Clipboard, Search History, and several other advanced features are temporarily unavailable. Corresponding Author. Institut für Pathologie, Tierärztliche Hochschule, Bunteweg 17, D‐30559 Hannover, Germany. Alldinger S, Fonfara S, Kremmer E, Baumgärtner W. Acta Neuropathol. eCollection 2020. USA.gov. Andreas Beineke Institut für Pathologie Tierärztliche Hochschule Hannover Prof. Dr. med. Miao Q, Baumgärtner W, Failing K, Alldinger S. Acta Neuropathol. Stiftung Tierärztliche Hochschule Hannover. Thus, intravenous application of this serotype 9 strain is required to evaluate heterologous protection in the course of vaccine development based on serotype 2 strains in the future. Ligation of CD44 in the early phase may induce chemokines and cytokines and hence initiate and perpetuate the inflammatory process. Up-regulation of the hyaluronate receptor CD44 in canine distemper demyelinated plaques. 2 Institut für Pathologie, Stiftung Tierärztliche Hochschule Hannover, M. Ganter. "Perfect place to start a veterinary career" Tierärztliche Hochschule Hannover Prof. Dr. med. Pathogenesis and immunopathology of systemic and nervous canine distemper. Comparative mRNA and miRNA expression in European mouflon (Ovis musimon) and sheep (Ovis aries) provides novel insights into the genetic mechanisms for female reproductive success. Stiftung Tierärztliche Hochschule Hannover. Willemse N, van der Ark KCH, Stockhofe-Zurwieden N, Smith H, Picavet DI, van Solt-Smits C, Wisselink HJ, Schultsz C, de Greeff A. Sci Rep. 2019 Oct 28;9(1):15429. doi: 10.1038/s41598-019-51576-0. Prevention and treatment information (HHS). 2009 Nov 18;139(3-4):310-7. doi: 10.1016/j.vetmic.2009.06.024. (3)Zentrum für Systemische Neurowissenschaften Hannover, ZSN. A 5-year-old German-Holstein cow was presented with a swelling of the head which had been present for 3 months. (4)4 Klinik für Heimtiere, Reptilien, Zier- und Wildvoegel, Stiftung Tieraerztliche Hochschule, Hannover… Institut für Pathologie, Tierärztliche Hochschule Hannover, Peter Wohlsein. Please enable it to take advantage of the complete set of features! Institut für Pathologie, Tierärztliche Hochschule Hannover › Author Affiliations › Further Information. Centre National des Listeria, Institut de Microbiologie, CHUV, CH‐19 Sud 1011, Lausanne, Switzerland . Epub 2003 Aug 15. doi: 10.1371/journal.pone.0152675. Would you like email updates of new search results? 2009 Jan 15;127(1-2):1-18. doi: 10.1016/j.vetimm.2008.09.023. Experimental intranasal and intravenous infections of 7-8 weeks old SPF piglets were investigated with regard to clinic and pathology. University Overview Founded in 1778, Tierärztliche Hochschule Hannover (University of Veterinary Medicine Hannover) is a non-profit public higher-education institution located in the urban setting of the large city of Hannover (population range of 500,000-1,000,000 inhabitants), Lower Saxony. | Porcine Health Manag. The principal histological findings were hyperkeratosis and epidermal hyperplasia. | Gutachter: Univ.-Prof. Marion Hewicker-Trautwein und PD Dr. med. Phase-dependent expression of matrix metalloproteinases and their inhibitors in demyelinating canine distemper encephalitis. Fittipaldi N, Fuller TE, Teel JF, Wilson TL, Wolfram TJ, Lowery DE, Gottschalk M. Vet Microbiol. In chronic lesions, CD44 expression declines together with the number of glial fibrillary acidic protein (GFAP) positive astrocytes. Institut für Pathologie, Tierärztliche Hochschule Hannover, Bünteweg 17, D‐3000 Hannover 71, Germany . Acta Neuropathol. 1 Klinik für kleine Klauentiere, forensische Medizin und Ambulatorische Klinik, Stiftung Tierärztliche Hochschule Hannover › Author Affiliations. 2005 Oct;110(4):369-82. doi: 10.1007/s00401-005-1055-z. Search for more papers by this author. In conclusion, this study demonstrates that MRP* SLY+ serotype 9 strains are less virulent for growers than MRP+ EF+ SLY+ serotype 2 strains. 2019 Feb;122(2):172-186. doi: 10.1038/s41437-018-0090-1. HHS Institut für Pathologie, Tierärztliche Hochschule Hannover, FRG. Universität Hannover, 2007. Lempp C, Spitzbarth I, Puff C, Cana A, Kegler K, Techangamsuwan S, Baumgärtner W, Seehusen F. Viruses. Carlos Hermosilla Institut für Parasitologie Proteomics Studies on the three Larval Stages of Development and Metamorphosis of Babylonia areolata. 1 Institut für Pathologie, Tierärztliche Hochschule Hannover, Germany. However, in Europe serotype 9 strains also contribute substantially to S. suis-associated invasive diseases of piglets. The working group „Behavioural ecology and conservation genetics“ aims to understand the factors, that drive and influence the evolution of social structures, the demographic composition, ecological niche construction, distribution, connectivity and the survival of populations. 2014 Jul 2;6(7):2571-601. doi: 10.3390/v6072571. 2020 May 6;6:12. doi: 10.1186/s40813-020-00150-6. Gutachten: Prof. Dr. med. Epub 2017 Nov 28. Epub 2009 Jun 21. Mol Med Rep. 2018 Feb;17(2):2161-2168. doi: 10.3892/mmr.2017.8177. Arwid Daugschies Institut für Parasitologie Veterinärmedizinische Fakultät der Universität Leipzig 2. Search Google Scholar for this author, R. Müller-Peddinghaus. Epub 2006 Jan 20. (2)2 Tieraerztliche Gemeinschaftspraxis Dres. 2006 Jun 15;115(1-3):117-27. doi: 10.1016/j.vetmic.2005.12.013. 2019 Oct 10;3:100046. doi: 10.1016/j.jvacx.2019.100046. Further Information. A. Navarro Camarro. Interestingly, expression of MRP within meningitis lesions was demonstrated for both pathotypes via immunohistochemistry. Stiftung Tierärztliche Hochschule Hannover. Corresponding Author . vorgelegt von Julia Menzel Stuttgart Hannover 2010 . To study the interactions between probiotic micro-organisms and the host their effects on morphology and mucins of the intestinal mucosa were investigated. J. Please enable it to take advantage of the complete set of features! Hannover und Umgebung, Deutschland Scientific Assistant at the Institute for Experimental Pathology of the Medical School Hannover (Director: Professor Dr. U. Mohr). TiHo Hannover - Institut für Pathologie Toxicologic Pathology Training Program A comprehensive Toxicologic Pathology Program is offered within the residency program of the TiHo. Canine distemper virus (CDV) belongs to the genus Morbillivirus of the Paramyxoviridae family. Corresponding Author. Epub 2016 Jun 30. Yang J, Li X, Cao YH, Pokharel K, Hu XJ, Chen ZH, Xu SS, Peippo J, Honkatukia M, Kantanen J, Li MH. Center for Systems Neuroscience, Stiftung Tierärztliche Hochschule Hannover, Medizinische Hochschule Hannover, ... Bedeutung für die molekulare Pathologie der Spinalen Muskelatrophie. vet.) In summary, CD44 and MMPs might be associated with the onset of demyelination and may interact to initiate ECM disturbances. The objective of this study was to determine the virulence of an MRP* SLY+ serotype 9 S. suis strain in comparison to an MRP+ EF+ SLY+ serotype 2 strain. 2010 Mar;18(3):124-31. doi: 10.1016/j.tim.2009.12.003. (1)Institut für Pathologie, Stiftung Tierärztliche Hochschule Hannover, D-30173 Hannover, Germany. 2009 Dec 15;132(2-4):135-45. doi: 10.1016/j.vetimm.2009.05.009. Epub 2008 Oct 4. PMID: 12016561 DOI: 10.1055/s-2002-30116 Abstract The mode of action of probiotics is still incompletely understood. Gregor Warnecke 2. Abstract; Full Text; References Buy Article Permissions and Reprints. Andrea Düngelhoef, Sophie Gschaider, Jana Seele, Nadine Büttner, and Christoph Hirche are acknowledged for their excellent work during their practicals. Abteilung für Experimentelle Pathologie, Dr. Karl Thomae GmbH, Biberach/Riß, und Institut für Pathologie, Abteilung für Immunpathologie, Tierärztliche Hochschule Hannover, Hannover, BRD See all articles by this author. in northwestern Madagasca. Beyerbach (Stiftung Tierärztliche Hochschule Hannover, Hannover, Germany) kindly provided support in statistical analysis. Tierärztliche Hochschule Hannover Population and molecular genetic analyses of persistent right aortic arch and primary cataracts in the German Pinscher INAUGURAL-DISSERTATION zur Erlangung des Grades einer Doktorin der Veterinärmedizin - Doctor medicinae veterinariae – (Dr. med. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. In contrast to the virulent serotype 2 strain, the serotype 9 strain did not cause disease with clinical manifestations after intranasal administration. Institut für Pathologie Tierärztliche Hochschule Hannover PD Dr. med. eCollection 2015. (2)Institut für Pathologie, Stiftung Tierärztliche Hochschule Hannover. Institute of Pathology, Section of Immunopathology and Institute of Virology, School of Veterinary Medicine, Hannover. Project: Effects of habitat fragmentation on parasite communities in mouse lemurs (Microcebus spp.) vet. Aerial photography: Department of Pathology. Office: Phone: 0049-(0)511- 953-8621; 0049-(0)511-953-8664 Fax: 0049-(0)511-953-8675 Diagnostic service section - consultation hours: Monday – Friday from 2.30 pm – 4.30 pm; phone: 0049-(0)511-953-8622 Aerial photography: Department of Pathology. Tenenbaum T, Asmat TM, Seitz M, Schroten H, Schwerk C. Future Microbiol. G. Trautwein. Role of Bacterial and Host DNases on Host-Pathogen Interaction during, A critical review speculating on the protective efficacies of autogenous, From Stable to Lab-Investigating Key Factors for Sudden Deaths Caused by, Vaccination with the immunoglobulin M-degrading enzyme of. Clonal expansion of a virulent Streptococcus suis serotype 9 lineage distinguishable from carriage subpopulations. In this phase, a decrease of MMP and TIMP expressions apart from MMP-11, -12, and -13 is obvious. Transcriptome analysis of the Capra hircus ovary. Stiftung Tierärztliche Hochschule Hannover. Rieckmann K, Pendzialek SM, Vahlenkamp T, Baums CG. New aspects of the pathogenesis of canine distemper leukoencephalitis. Research topics. The program is subdivided into different seminars (modules) and receives support from speakers from Pharmaceutical and Chemical companies mainly located in Germany. 6 Kliniken, 19 Institute, 3 Fachgebiete und 3 Außenstellen gehören zur Stiftung Tierärztliche Hochschule Hannover. The University of Veterinary Medicine Hannover, Foundation (TiHo) is a nationally and internationally recognized institution of higher education known for its excellence in veterinary science and its interdisciplinary focus. However, histological screenings of these animals revealed pathological lesions, such as mild focal suppurative meningitis. R. Müller-Peddinghaus . The skin lesions were divided into four macroscopic groups: scaling (group I, n = 5), hyperkeratotic and hyperplastic plaque‐like lesions (group II, n = 14), nodular skin masses (group III, n = 16) and verrucous skin lesions (group IV, n = 2). Shen M, Di G, Li M, Fu J, Dai Q, Miao X, Huang M, You W, Ke C. Sci Rep. 2018 Apr 19;8(1):6269. doi: 10.1038/s41598-018-24645-z. 2015 Mar 30;10(3):e0121586. … Clinical examination revealed a 15 × 20 × 15 cm firm … Institut für Pathologie der Tierärztlichen Hochschule Hannover, Bünteweg 17, D‐3000 Hannover 71, Germany. Virulence-associated gene profiling of Streptococcus suis isolates by PCR. Zhao ZQ, Wang LJ, Sun XW, Zhang JJ, Zhao YJ, Na RS, Zhang JH. Zusammenfassung. 2016 Apr 4;11(4):e0152675. eCollection 2016. Trends Microbiol. (3)3 Institut für Pathologie der Stiftung Tieraerztliche Hochschule Hannover, Hannover, Germany. The University of Veterinary Medicine Hanover (German: Tierärztliche Hochschule Hannover, TiHo) is a university in Hanover and one of the five facilities for veterinary medicine in Germany, and the only one that remains independent. In acute and subacute CDE, a plaque-associated CD44 up-regulation is found that parallels astrocyte activation. Due to the central nervous system (CNS) tropism of the virus and associated neuropathological changes, demyelinating canine distemper encephalitis (CDE) represents a relevant model for human demyelinating diseases like multiple sclerosis. Kock C, Beineke A, Seitz M, Ganter M, Waldmann KH, Valentin-Weigand P, Baums CG. | In the chronic phase, it is conceivable that a MMP-TIMP imbalance may be the motor for lesion progression with a simultaneous influx of CD44-positive activated immune cells. Save as PDF. Studies on pathogenesis as well as vaccine trials have focused on serotype 2 strains, which are worldwide the most prevalent among invasive isolates. Meurer M, Öhlmann S, Bonilla MC, Valentin-Weigand P, Beineke A, Hennig-Pauka I, Schwerk C, Schroten H, Baums CG, Köckritz-Blickwede MV, de Buhr N. Int J Mol Sci. Rieckmann K, Seydel A, Klose K, Alber G, Baums CG, Schütze N. Vaccine X. Doctoral student . Up-regulation of mRNA for matrix metalloproteinases-9 and -14 in advanced lesions of demyelinating canine distemper leukoencephalitis. D-30559 Hannover, Germany e-mail: Send e-mail . NIH See 3 photos and 3 tips from 80 visitors to Tierärztliche Hochschule Hannover. Intranasal immunization with a live Streptococcus suis isogenic ofs mutant elicited suilysin-neutralization titers but failed to induce opsonizing antibodies and protection. Author information: (1)Klinik für Rinder, Stiftung Tierärztliche Hochschule Hannover. : 0511 / 953-8621 , 0511 / 953-8664 Diagnostik-Sprechstunden: Mo. Medizinische Hochschule Hannover, 2006. Friederike Döring: Die intrazelluläre Lokalisation von Isoformen des Fibroblastenwachstumsfaktors – 2 (FGF-2). COVID-19 is an emerging, rapidly evolving situation. Bacteriological culture and immunohistochemistry of the brain confirmed association with the S. suis challenge strains in all cases with clinical manifestations. Toward Understanding the Genetic Basis of Yak Ovary Reproduction: A Characterization and Comparative Analyses of Estrus Ovary Transcriptiome in Yak and Cattle. Heredity (Edinb). Silva LM, Baums CG, Rehm T, Wisselink HJ, Goethe R, Valentin-Weigand P. Vet Microbiol. In addition, in this plaque type, CD44 is expressed on the cell membrane of perivascular mononuclear cells. Clipboard, Search History, and several other advanced features are temporarily unavailable. Beineke A, Puff C, Seehusen F, Baumgärtner W. Vet Immunol Immunopathol. Biological activities of suilysin: role in Streptococcus suis pathogenesis. Streptococcus (S.) suis is an invasive porcine pathogen causing meningitis, septicemia, arthritis and other diseases.
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